Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513395 | 1.00 | HDAC1 (0.79) | HDAC1HDAC8HDAC6 | |
| SCHEMBL6513390 | 1.00 | HDAC1 (0.79) | HDAC1HDAC8HDAC6 | |
| SCHEMBL6512867 | 0.91 | HDAC1 (0.76) | HDAC1HDAC8HDAC6 | |
| SCHEMBL6512864 | 0.91 | HDAC1 (0.76) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5566777 | 0.88 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5560902 | 0.88 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5566770 | 0.88 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5560896 | 0.88 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5560899 | 0.88 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL6532814 | 0.82 | HDAC1 (0.89) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137234-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2005-06-23 | — | — | US | claimed |
| WO-2005066151-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050137234-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137234-A1 | Histone deacetylase inhibitors | HDAC1, HDAC5, HDAC11 | HDAC1 1/4885HDAC8 7/4885HDAC6 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.