Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19927107 | 1.00 | LPAR3 (0.52) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL19926726 | 1.00 | LPAR3 (0.52) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL23671717 | 0.92 | LPAR3 (0.45) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL21152326 | 0.85 | CA12 (0.41) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL3239278 | 0.84 | LPAR2 (0.44) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL11329860 | 0.83 | KDM4E (0.59) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL22906226 | 0.82 | CA12 (0.42) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL25358059 | 0.80 | LPAR3 (0.47) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL23451051 | 0.80 | MEN1 (0.59) | LPAR3LPAR2LPAR1S1PR1S1PR3 | |
| SCHEMBL9697062 | 0.80 | LPAR3 (0.47) | LPAR3LPAR2LPAR1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572246-A2 | NOVEL COMPOSITIONS OF MAGNETIC PARTICLES COVERED WITH GEM-BISPHOSPHONATE DERIVATIVES | GUERBET (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004058275-A2 | COMPOSITIONS OF MAGNETIC PARTICLES COVERED WITH GEM-BISPHOSPHONATE DERIVATIVES | GUERBET (FR) | 2004-07-15 | — | — | WO | disclosed |