Isobutylbenzene

Isobutylbenzene

SCHEMBL6514302

CC(C)Cc1ccccc1.CC(N)=O

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
XIAP P98170 1/20 0.59
SLC7A5 Q01650 1/20 0.59
EPHX1 P07099 2/20 0.56
SLC6A2 P23975 2/20 0.54
TAAR1 Q96RJ0 2/20 0.54
MAOA P21397 1/20 0.54
SLC6A4 P31645 1/20 0.54
SLC6A3 Q01959 1/20 0.54
SIGMAR1 Q99720 1/20 0.54
CYP2A6 P11509 1/20 0.54
ADORA2A P29274 1/20 0.54
ADORA1 P30542 1/20 0.54
PTGS2 P35354 3/20 0.53
LMNA P02545 2/20 0.53
CYP2C9 P11712 2/20 0.53
AKR1C3 P42330 2/20 0.53
CXCR1 P25024 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutylbenzene SCHEMBL5343232 0.94 EPHX1 (0.58) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL6648882 0.91 PTGS1 (0.57) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL28116998 0.91 PTGS1 (0.57) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL27782096 0.90 PTGS1 (0.53) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL27955709 0.89 PTGS1 (0.59) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL7038219 0.88 EPHX1 (0.53) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL363626 0.87 TAAR1 (0.61) PTGS1EPHX1SLC6A2TAAR1MAOA
Isobutylbenzene SCHEMBL27893386 0.86 NPC1 (0.53) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL27335089 0.86 PTGS1 (0.52) PTGS1ALPIPKMXIAPSLC7A5
Isobutylbenzene SCHEMBL27819966 0.86 PTGS1 (0.62) PTGS1ALPIPKMXIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050256017-A1 Fast-acting formulation components, compositions and laundry methods employing same THE PROCTER & GAMBLE COMPANY (US) 2005-11-17 US disclosed
US-20050070454-A1 Fast-acting formulation components, compositions and laundry methods employing same THE PROCTER & GAMBLE COMPANY (US) 2005-03-31 US disclosed
EP-1206520-A1 FAST-ACTING FORMULATION COMPONENTS, COMPOSITIONS AND LAUNDRY METHODS EMPLOYING SAME THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP disclosed
WO-2001016275-A1 FAST-ACTING FORMULATION COMPONENTS, COMPOSITIONS AND LAUNDRY METHODS EMPLOYING SAME THE PROCTER & GAMBLE COMPANY (US) 2001-03-08 WO disclosed