SCHEMBL6514801

SCHEMBL6514801

O=c1ccn([C@H]2O[C@@H](CO)C(O)C2OOCF)c(=O)[nH]1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.67
▸ SLC28A2 O43868 1/20 0.67
▸ SLC29A1 Q99808 1/20 0.67
▸ SLC28A3 Q9HAS3 1/20 0.67
▸ P2RY14 Q15391 8/20 0.49
▸ P2RY2 P41231 8/20 0.48
▸ P2RY6 Q15077 8/20 0.48
▸ P2RY4 P51582 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5420941 0.90 SLC28A1 (0.71) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL20815980 0.90 SLC28A1 (0.71) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL23856021 0.86 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL93615 0.86 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL23856022 0.86 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL1255107 0.86 SLC28A1 (0.73) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL20732056 0.86 SLC28A1 (0.73) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL30132739 0.86 SLC28A1 (0.73) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL233417 0.86 SLC28A1 (0.73) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL7190661 0.86 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050266422-A1 Fluoroalkoxy, nucleosides, nucleotides, and polynucleotides SIRNA THERAPEUTICS, INC. (US) 2005-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050266422-A1 Fluoroalkoxy, nucleosides, nucleotides, and polynucleotides NSUN3, IRF3, SNRPF SLC28A1 296/4885SLC28A2 400/4885SLC29A1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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