Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of 3-Methylpyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylpyridine SCHEMBL30529819 | 1.00 | CYP2A6 (0.52) | — | |
| 3-Methylpyridine SCHEMBL6509626 | 1.00 | — | — | |
| 3-Methylpyridine SCHEMBL1451326 | 0.97 | CYP2A6 (0.50) | — | |
| 3-Methylpyridine SCHEMBL28392462 | 0.97 | — | — | |
| 3-Methylpyridine SCHEMBL29361018 | 0.97 | — | — | |
| 3-Methylpyridine SCHEMBL10530 | 0.97 | — | — | |
| 3-Methylpyridine SCHEMBL820155 | 0.97 | CYP2A6 (0.54) | — | |
| 3-Methylpyridine SCHEMBL493021 | 0.94 | CYP2A6 (0.52) | — | |
| 3-Methylpyridine SCHEMBL3957265 | 0.94 | — | — | |
| 3-Methylpyridine SCHEMBL4759127 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240021887-A1 | ELECTROLYTE FOR AQUEOUS ZINC-BROMINE BATTERY CONTAINING BROMINE COMPLEXING AGENT AND METAL ION ADDITIVE, AND AQUEOUS ZINC-BROMINE NON-FLOW BATTERY CONTAINING SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2024-01-18 | — | — | US | claimed |
| WO-2005066129-A2 | BIS-PYRIDINO CONTAINING COMPOUNDS FOR USE IN THE TREATMENT OF CNS PATHOLOGIES | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2005-07-21 | — | — | WO | claimed |
| US-5691365-A | Nicotinic receptor antagonists in the treatment of neuropharmacological disorders | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1997-11-25 | — | — | US | claimed |
| CN-117659010-A | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20240021887-A1 | ELECTROLYTE FOR AQUEOUS ZINC-BROMINE BATTERY CONTAINING BROMINE COMPLEXING AGENT AND METAL ION ADDITIVE, AND AQUEOUS ZINC-BROMINE NON-FLOW BATTERY CONTAINING SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2024-01-18 | — | — | US | disclosed |
| CN-111867581-B | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114566723-A | Electrolyte for rechargeable electrochemical cells | EOS能源储存有限责任公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-109155444-B | Electrolyte for rechargeable electrochemical cells | EOS能源储存有限责任公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-111072451-B | Hydrolysis process of Grignard reaction metal organic product | 上虞新和成生物化工有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-111072451-A | Green hydrolysis process of Grignard reaction metal organic product | 上虞新和成生物化工有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-106149414-B | The preparation method of ionic liquid carbon conductive nano solution and Far-infrared radiation heating material | 中国科学院过程工程研究所 | 2019-05-24 | — | — | CN | disclosed |
| WO-2015183530-A1 | NICOTINE DERIVATIVES AND METHODS OF USE | GOODMAN JORY F (US) | 2015-12-03 | — | — | WO | disclosed |
| EP-2758373-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | Bromine Compounds Ltd. (IL) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013042109-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | BROMINE COMPOUNDS LTD. (IL) | 2013-03-28 | — | — | WO | disclosed |
| CN-101010339-B | Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO | 2011-11-09 | — | — | CN | disclosed |
| CN-100513405-C | Chiral ionic compound containing pyrrolidinyl radical and its preparation and application | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-07-15 | — | — | CN | disclosed |
| CN-101010339-A | Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2007-08-01 | — | — | CN | disclosed |
| CN-1974566-A | Chiral ionic compound containing pyrrolidinyl radical and its prepn and application | UNIV ZHEJIANG POLYTECHNIC (CN) | 2007-06-06 | — | — | CN | disclosed |
| US-5691365-A | Nicotinic receptor antagonists in the treatment of neuropharmacological disorders | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1997-11-25 | — | — | US | disclosed |
| US-4100100-A | THIOCYANATE OR THIOAMIDE, QUATERNARY PYRIDINIUM, COBALT | THE DOW CHEMICAL COMPANY (US) | 1978-07-11 | — | — | US | disclosed |