Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.58 |
| ▸ | PPARG | P37231 | 13/20 | 0.58 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511438 | 0.92 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6512166 | 0.92 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6513058 | 0.92 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6528547 | 0.91 | PPARA (0.48) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3844826 | 0.90 | PPARA (0.55) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3842008 | 0.89 | PPARA (0.54) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3841453 | 0.89 | PPARA (0.54) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3286740 | 0.89 | PPARA (0.54) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL6514551 | 0.89 | PPARA (0.62) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3842820 | 0.88 | PPARA (0.53) | PPARAPPARGPPARDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | claimed |