Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652415 | 0.93 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL653897 | 0.91 | MAPT (0.40) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL653370 | 0.90 | MAPT (0.40) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176547 | 0.88 | MAPT (0.47) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL699657 | 0.87 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL650770 | 0.87 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL654745 | 0.87 | MAPT (0.38) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176532 | 0.86 | PTPN7 (0.44) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176434 | 0.86 | HPGD (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL703259 | 0.86 | MEN1 (0.38) | MAPTL3MBTL1MAPK1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 886 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003990-A | Heterocyclic amine Hedgehog signal path inhibitor | JIANGSU SIMCERE PHARM RES CO | 2014-08-27 | — | — | CN | claimed |
| CN-101910168-B | Tropane compounds | EXELIXIS INC | 2014-07-30 | — | — | CN | claimed |
| CN-103910736-A | Dihydropyran pyrimidine derivatives and pharmaceutical application thereof | JIANGSU SIMCERE PHARM RES CO | 2014-07-09 | — | — | CN | claimed |
| CN-101896507-B | Catalyst compounds and their use | EXXONMOBIL CHEM PATENTS INC | 2012-11-28 | — | — | CN | claimed |
| CN-102516184-A | DPP-IV inhibitor including beta-amino group, preparation method thereof and pharmaceutical composition containing the same for preventing and treating a diabetes or an obesity | DONG A PHARM CO LTD | 2012-06-27 | — | — | CN | claimed |
| CN-102171210-A | Imidazopyridin-2-one derivatives | DAIICHI SANKYO CO LTD | 2011-08-31 | — | — | CN | claimed |
| CN-102149676-A | Mono-aryl aminotetralines | HOFFMANN LA ROCHE | 2011-08-10 | — | — | CN | claimed |
| CN-102037007-A | Selective exosite inhibition of PAPP-A activity against IGFBP-4 | UNIV AARHUS | 2011-04-27 | — | — | CN | claimed |
| CN-101981013-A | Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors | JANSSEN PHARMACEUTICA NV | 2011-02-23 | — | — | CN | claimed |
| CN-101910168-A | Tropane compounds | EXELIXIS INC | 2010-12-08 | — | — | CN | claimed |
| CN-1344718-A | New phthalocyanine derivative and its application | BIN YUEJING (CN) | 2002-04-17 | — | — | CN | claimed |
| CN-1072237-C | Polymerization catalyst for alkylene oxide and process for producing poly | MITSUI TOATSU CHEMICALS (JP) | 2001-10-03 | — | — | CN | claimed |
| CN-1265115-A | Streptogramines, their prepn. and compsns. containing them | RHONE POULENC RORER SA (FR) | 2000-08-30 | — | — | CN | claimed |
| CN-1231668-A | 2-heteroatom substituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW CHEMICAL CO (US) | 1999-10-13 | — | — | CN | claimed |
| CN-1230187-A | Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors | GLAXO GROUP LTD (GB) | 1999-09-29 | — | — | CN | claimed |
| CN-1230190-A | 3-heteroatom sustituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | CN | claimed |
| CN-1169742-A | Molding material and molded motor | MATSUSHITA ELECTRIC IND C LTD (JP) | 1998-01-07 | — | — | CN | claimed |
| CN-1151414-A | Polymerization catalyst for alkylene oxide and process for producing poly | MITSUI TOATSU CHEMICALS (JP) | 1997-06-11 | — | — | CN | claimed |
| CN-1145068-A | Substituted sulphonylaminocarbonyltriazolinones and their use as herbicides | BAYER AG (DE) | 1997-03-12 | — | — | CN | claimed |
| CN-1123546-A | 4-arylisoindole analgesics | ORTHO PHARMA CORP (US) | 1996-05-29 | — | — | CN | claimed |