Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511481 | 0.97 | PPARA (0.47) | PPARAPPARGTLR7PPARDGRM2 | |
| SCHEMBL6508874 | 0.97 | PPARA (0.47) | PPARAPPARGTLR7PPARDGRM2 | |
| SCHEMBL6508372 | 0.92 | PPARA (0.51) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6513188 | 0.92 | PPARA (0.51) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6512124 | 0.89 | PPARA (0.51) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6531406 | 0.88 | PPARA (0.48) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6516974 | 0.88 | PPARA (0.48) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6509723 | 0.87 | PPARA (0.50) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6508401 | 0.86 | PPARA (0.49) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6514556 | 0.86 | PPARA (0.49) | PPARAPPARGTLR7PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |