Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939426 | 0.98 | METAP1 (0.51) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1162229 | 0.98 | METAP1 (0.51) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3996259 | 0.87 | METAP1 (0.41) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4001294 | 0.87 | METAP1 (0.41) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4000605 | 0.87 | METAP1 (0.41) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1814190 | 0.85 | METAP1 (0.44) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1817699 | 0.85 | METAP1 (0.44) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3994705 | 0.85 | METAP1 (0.44) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3967280 | 0.83 | METAP1 (0.41) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3958014 | 0.83 | METAP1 (0.41) | METAP1ALDH1A1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009151-A1 | Methods for the stereospecific and enantiomeric enrichment of beta-amino acids | PHARMACIA CORPORATION | 2005-01-13 | — | — | US | disclosed |