Hydroxyamine

Hydroxyamine

SCHEMBL6517648

CC(O)CN(CCO)CC(C)O.NO

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 2/20 0.35
KDM4E B2RXH2 3/20 0.34
TSHR P16473 4/20 0.32
RECQL P46063 1/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1144943 0.97 TDP1 (0.40) TDP1MAPTKDM4ETSHRRECQL
SCHEMBL20216922 0.97 TDP1 (0.40) TDP1MAPTKDM4ETSHRRECQL
Hydrochloric Acid SCHEMBL29482286 0.95 TDP1 (0.38) TDP1MAPTKDM4ETSHRRECQL
SCHEMBL10180673 0.92 TDP1 (0.36) TDP1MAPTKDM4ETSHRRECQL
Edetol SCHEMBL10874369 0.92 TDP1 (0.36) TDP1MAPTKDM4ETSHRRECQL
SCHEMBL344219 0.92 TDP1 (0.36) TDP1MAPTKDM4ETSHRRECQL
SCHEMBL20994688 0.92 TDP1 (0.40) TDP1MAPTKDM4ETSHRRECQL
SCHEMBL131477 0.92 TDP1 (0.40) TDP1MAPTKDM4ETSHRRECQL
SCHEMBL4749725 0.90 KDM4E (0.35) TDP1MAPTKDM4ETSHRRECQL
Boric Acid SCHEMBL19348517 0.90 TDP1 (0.35) TDP1MAPTKDM4ETSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1019334-B1 USE OF HYDROXYLAMINES TO ENHANCE THE STRENGTH OF PORTLAND CEMENT COMPOSITIONS GRACE W R & CO (US) 2005-12-28 EP claimed