⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263952 | 0.91 | CES1 (0.33) | — | |
| SCHEMBL31210100 | 0.79 | CES1 (0.36) | — | |
| SCHEMBL29838385 | 0.76 | CES1 (0.31) | — | |
| SCHEMBL29838355 | 0.76 | CES1 (0.31) | — | |
| SCHEMBL9411720 | 0.76 | CES1 (0.31) | — | |
| SCHEMBL29838517 | 0.74 | CES1 (0.32) | — | |
| SCHEMBL29394885 | 0.74 | — | — | |
| SCHEMBL29397607 | 0.74 | — | — | |
| SCHEMBL18092846 | 0.74 | CYP1A2 (0.34) | — | |
| SCHEMBL6859937 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921636-B1 | Method and apparatus for conducting an array of chemical reactions on a support surface | METRIGEN, INC. (US) | 2005-07-26 | — | — | US | disclosed |
| EP-1159285-B1 | METHODS AND COMPOSITIONS FOR ECONOMICALLY SYNTHESIZING AND ASSEMBLING LONG DNA SEQUENCES | METRIGEN INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20050009092-A1 | Method and apparatus for conducting an array of chemical reactions on a support surface | BRENNAN THOMAS M (US) | 2005-01-13 | — | — | US | disclosed |
| US-20030186226-A1 | Methods and compositions for economically synthesizing and assembling long DNA sequences | MOLINARI, ROBERT J., PH.D. AS COLLATERAL AGENT | 2003-10-02 | — | — | US | disclosed |
| US-20030068643-A1 | Methods and compositions for economically synthesizing and assembling long DNA sequences | BRENNAN THOMAS M (US) | 2003-04-10 | — | — | US | disclosed |
| US-6210894-B1 | Method and apparatus for conducting an array of chemical reactions on a support surface | PROTOGENE LABORATORIES, INC. | 2001-04-03 | — | — | US | disclosed |
| US-5985551-A | Method and apparatus for conducting an array of chemical reactions on a support surface | PROTOGENE LABORATORIES, INC. (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0703825-B1 | METHOD AND APPARATUS FOR CONDUCTING AN ARRAY OF CHEMICAL REACTIONS ON A SUPPORT SURFACE | PROTOGENE LAB INC (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5474796-A | Immobilization | PROTOGENE LABORATORIES, INC. (US) | 1995-12-12 | — | — | US | disclosed |