Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 14/20 | 0.81 |
| ▸ | CDK2 | P24941 | 13/20 | 0.81 |
| ▸ | CDK9 | P50750 | 13/20 | 0.81 |
| ▸ | CDK1 | P06493 | 13/20 | 0.81 |
| ▸ | CCND1 | P24385 | 12/20 | 0.81 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.81 |
| ▸ | CCNB1 | P14635 | 10/20 | 0.81 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.81 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.81 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.81 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.81 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.81 |
| ▸ | CCND3 | P30281 | 4/20 | 0.81 |
| ▸ | GSK3A | P49840 | 4/20 | 0.81 |
| ▸ | CDK7 | P50613 | 3/20 | 0.81 |
| ▸ | CCNH | P51946 | 2/20 | 0.81 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.81 |
| ▸ | MAPK15 | Q8TD08 | 2/20 | 0.81 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.81 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180351 | 1.00 | CDK4 (0.81) | CDK4CDK2CDK9CDK1CCND1 | |
| SCHEMBL1180345 | 1.00 | CDK4 (0.81) | CDK4CDK2CDK9CDK1CCND1 | |
| SCHEMBL1180348 | 1.00 | CDK4 (0.81) | CDK4CDK2CDK9CDK1CCND1 | |
| SCHEMBL27028149 | 0.93 | CDK4 (0.81) | CDK4CDK2CDK9CDK1CCND1 | |
| SCHEMBL1180211 | 0.92 | CDK4 (0.82) | CDK4CDK2CDK9CDK1CCND1 | |
| SCHEMBL1180222 | 0.92 | CDK4 (0.82) | CDK4CDK2CDK9CDK1CCND1 | |
| SCHEMBL1180213 | 0.92 | CDK4 (0.82) | CDK4CDK2CDK9CDK1CCND1 | |
| Hydrochloric Acid SCHEMBL1180102 | 0.91 | CDK4 (0.82) | CDK4CDK2CDK9CDK1CCND1 | |
| Hydrochloric Acid SCHEMBL1180106 | 0.91 | CDK4 (0.82) | CDK4CDK2CDK9CDK1CCND1 | |
| Hydrochloric Acid SCHEMBL1180100 | 0.91 | CDK4 (0.82) | CDK4CDK2CDK9CDK1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556375-A2 | FLAVONE DERIVATIVES AS INHIBITORS OF CYCLIN-DEPENDENT KINASES | Nicholas Piramal India Limited (IN) | 2005-07-27 | — | — | EP | claimed |
| WO-2004004632-A2 | FLAVONE DERIVATIVES AS INHIBITORS OF CYCLIN-DEPENDENT KINASES | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2004-01-15 | — | — | WO | claimed |