Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 8/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 5/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159637 | 0.92 | SYK (0.41) | SYKMAP3K12 | |
| SCHEMBL1159228 | 0.92 | SYK (0.40) | SYKMAP3K12KITFLT3MAP2K1 | |
| SCHEMBL1158643 | 0.91 | SYK (0.41) | SYKMAP3K12TYK2 | |
| SCHEMBL1159717 | 0.90 | SYK (0.39) | SYKMAP3K12KITFLT3MAP2K1 | |
| SCHEMBL1159250 | 0.90 | SYK (0.41) | SYKMAP3K12TYK2 | |
| SCHEMBL1158692 | 0.89 | SYK (0.39) | SYKTYK2 | |
| SCHEMBL1158537 | 0.89 | SYK (0.42) | SYKMAP3K12KITFLT3TYK2 | |
| SCHEMBL6519251 | 0.89 | SYK (0.40) | SYKMAP3K12MAP2K1TYK2 | |
| SCHEMBL1158681 | 0.87 | SYK (0.39) | SYKMAP3K12TYK2 | |
| SCHEMBL1158733 | 0.86 | SYK (0.40) | SYKMAP3K12KITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | US | claimed |
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | SYK, BTK, LYN | SYK 1/4885MAP3K12 135/4885KIT 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.