Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 3/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649799 | 1.00 | PTPN11 (0.45) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL651590 | 0.84 | NPC1 (0.54) | KMT2AMEN1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL649125 | 0.84 | NPC1 (0.54) | KMT2AMEN1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL650783 | 0.83 | CSNK2A2 (0.49) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL652094 | 0.83 | OGA (0.42) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL652095 | 0.83 | OGA (0.42) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL651291 | 0.82 | OGA (0.47) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL650970 | 0.82 | MAPT (0.41) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL651290 | 0.82 | OGA (0.47) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL651253 | 0.82 | MAPT (0.41) | PTPN11KMT2AMEN1APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013240-B1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO LTD (JP) | 2017-05-31 | — | — | EP | disclosed |
| US-8492511-B2 | Process for the preparation of crosslinked nitroxide polymers | PIOTREK CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| US-8252862-B2 | Silane coupling agents for filled rubbers | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| EP-2190912-B1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2011-11-23 | — | — | EP | disclosed |
| EP-1945705-B1 | PHOTOLATENT SYSTEMS | BASF SE (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-7902368-B2 | Cationic substituted 2,2,6,6-tetraalkylpiperidinyl alkoxyamines | BASF SE (DE) | 2011-03-08 | — | — | US | disclosed |
| US-7868171-B2 | N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators | CIBA SPECIALTY CHEMICALS CORP. (US) | 2011-01-11 | — | — | US | disclosed |
| WO-2004022617-A1 | METHOD OF PRODUCING COMB OR STAR COPOLYMERS USING EPOXY-FUNCTIONALIZED NITROXYLETHERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-18 | — | — | WO | disclosed |
| EP-1397349-A1 | 4-IMINO-N-ALKOXY OR OXY-POLYALKYL-PIPERIDINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | Ciba SC Holding AG (CH) | 2004-03-17 | — | — | EP | disclosed |
| US-20040049043-A1 | N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization | CIBA SPECIALTY CHEMICALS CORP. | 2004-03-11 | — | — | US | disclosed |
| WO-2004000809-A1 | CATIONIC ALKOXYAMINES AND THEIR USE IN PRODUCING NANO PARTICLES FROM NATURAL OR SYNTHETIC CLAYS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-12-31 | — | — | WO | disclosed |
| EP-1343827-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | Ciba SC Holding AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| WO-2003075091-A1 | COLOUR PHOTOGRAPHIC RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-12 | — | — | WO | disclosed |
| EP-1341763-A2 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION | Ciba SC Holding AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002100831-A1 | 4-IMINO-N-ALKOXY OR OXY-POLYALKYL-PIPERIDINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002048109-A2 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002048205-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | CDC7, CDK17, CDCA2 | PTPN11 1970/4885KMT2A 3437/4885MEN1 1406/4885 |
| US-20040049043-A1 | N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization | PAOX, ALKBH3, PTGER4 | PTPN11 4189/4885KMT2A 1176/4885MEN1 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.