SCHEMBL6521580

SCHEMBL6521580

CCCCCCOc1ccc(-c2nc(-c3ccc(OC)cc3)nc(-c3ccc(OC)cc3)n2)c(O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 3/20 0.49
NR5A1 Q13285 1/20 0.49
NPC1 O15118 2/20 0.47
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
GPR35 Q9HC97 1/20 0.46
GPR55 Q9Y2T6 1/20 0.46
HTT P42858 1/20 0.46
RARB P10826 3/20 0.45
ALDH2 P05091 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LTA4H P09960 1/20 0.43
MGLL Q99685 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29638853 1.00 PTPN11 (0.49) PTPN11NR5A1NPC1LMNAMAPT
SCHEMBL791340 1.00 PTPN11 (0.49) PTPN11NR5A1NPC1LMNAMAPT
SCHEMBL3813335 0.96 NPC1 (0.50) PTPN11NPC1LMNAMAPTCNR1
SCHEMBL23285271 0.94 PTPN11 (0.46) PTPN11NR5A1NPC1LMNAMAPT
SCHEMBL26915684 0.92 PTPN11 (0.50) PTPN11NR5A1NPC1LMNAMAPT
SCHEMBL29364333 0.90 PTPN11 (0.49) PTPN11NR5A1NPC1MAPTCNR2
SCHEMBL3675957 0.90 PTPN11 (0.49) PTPN11NR5A1NPC1MAPTCNR2
SCHEMBL4413556 0.90 PTPN11 (0.49) PTPN11NR5A1NPC1MAPTCNR2
SCHEMBL39014 0.90 PTPN11 (0.49) PTPN11NR5A1NPC1MAPTCNR2
SCHEMBL7894761 0.90 PTPN11 (0.49) PTPN11NR5A1NPC1MAPTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834304-B1 Use of liposomogenic UV absorbers to protect hair CIBA SC HOLDING AG (CH) 2005-01-26 EP disclosed
EP-0654469-B1 Stabilised polymers containing o-hydroxyphenyl-s-triazines CIBA SC HOLDING AG (CH) 2001-08-22 EP disclosed
EP-0815071-B1 LIPOSOMOGENIC UV ABSORBERS CIBA SC HOLDING AG (CH) 2001-04-11 EP disclosed
US-6017556-A PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-25 US disclosed
US-6015575-A TRIAZINE, BENZOTRIAZOLE, BENZOPHENONE AND AMINOBENZOIC ACID DERIVATIVES AS RADIATION ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-18 US disclosed
EP-0834304-A2 Liposomogenic UV absorbers Ciba SC Holding AG (CH) 1998-04-08 EP disclosed
US-5688995-A SUNSCREEN AGENTS CIBA-GEIGY CORPORATION (US) 1997-11-18 US disclosed
US-5591850-A STABILIZERS FOR TEXTILE FIBERS, COSMETIC SUNSCREENS CIBA-GEIGY CORPORATION (US) 1997-01-07 US disclosed
EP-0743309-A1 o-Hydroxyphenyl-s-triazines as UV stabilisers CIBA-GEIGY AG (CH) 1996-11-20 EP disclosed
EP-0654469-A1 O-Hydroxyphenyl-s-triazines as stabilisers for polymers CIBA-GEIGY AG (CH) 1995-05-24 EP disclosed