Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | TYK2 | P29597 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.34 |
| ▸ | BCL6 | P41182 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1158927 | 0.90 | SYK (0.41) | SYKTYK2BCL6NCOR2 | |
| SCHEMBL6518376 | 0.90 | TYK2 (0.42) | SYKTYK2GRM2MAP2K1 | |
| SCHEMBL12797186 | 0.86 | SYK (0.38) | SYKTYK2BCL6NCOR2 | |
| SCHEMBL1158485 | 0.85 | SYK (0.40) | SYKTYK2MAP2K1 | |
| SCHEMBL1158713 | 0.83 | SYK (0.54) | SYKGRM2 | |
| SCHEMBL1159049 | 0.82 | SYK (0.41) | SYKGRM2BCL6NCOR2 | |
| SCHEMBL1158872 | 0.80 | TYK2 (0.37) | SYKTYK2BCL6NCOR2 | |
| SCHEMBL1158907 | 0.79 | TYK2 (0.43) | SYKTYK2 | |
| SCHEMBL1159077 | 0.77 | SYK (0.42) | SYKTYK2GRM2MAP2K1 | |
| SCHEMBL1158393 | 0.77 | SYK (0.42) | SYKTYK2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | US | claimed |
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | US | disclosed |
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | US | disclosed |
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053897-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | SYK, BTK, LYN | SYK 1/4885TYK2 35/4885GRM2 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.