Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155254 | 1.00 | IGF1R (0.45) | IGF1RUSP30PIK3CDBTKHDAC4 | |
| SCHEMBL6523000 | 1.00 | IGF1R (0.45) | IGF1RUSP30PIK3CDBTKHDAC4 | |
| SCHEMBL2331346 | 0.94 | IGF1R (0.48) | IGF1RUSP30PIK3CDBTKCNR1 | |
| SCHEMBL2331342 | 0.94 | IGF1R (0.48) | IGF1RUSP30PIK3CDBTKCNR1 | |
| SCHEMBL31664319 | 0.94 | IGF1R (0.48) | IGF1RUSP30PIK3CDBTKCNR1 | |
| SCHEMBL16513312 | 0.90 | USP30 (0.45) | USP30PIK3CDBTKHDAC4HDAC6 | |
| SCHEMBL18563163 | 0.90 | USP30 (0.45) | USP30PIK3CDBTKHDAC4HDAC6 | |
| SCHEMBL14672555 | 0.89 | JAK3 (0.48) | USP30PIK3CDBTKHDAC4HDAC6 | |
| SCHEMBL14672554 | 0.89 | JAK3 (0.48) | USP30PIK3CDBTKHDAC4HDAC6 | |
| SCHEMBL20154901 | 0.88 | IGF1R (0.45) | IGF1RUSP30PIK3CDBTKHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618103-B2 | Inhibitors of JAK | HOFFMANN-LA ROCHE INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20110059118-A1 | INHIBITORS OF JAK | DE VICENTE FIDALGO JAVIER | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059118-A1 | INHIBITORS OF JAK | JAK1, JAK3, JAK2 | IGF1R 1990/4885USP30 1006/4885PIK3CD 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.