Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.41 |
| ▸ | GPR6 | P46095 | 13/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6521585 | 0.88 | GPR6 (0.36) | GPR6 | |
| SCHEMBL6524778 | 0.88 | GPR6 (0.46) | GPR6 | |
| SCHEMBL6523336 | 0.87 | GPR6 (0.38) | GPR6HRH1CCR3 | |
| SCHEMBL6524594 | 0.87 | HRH1 (0.46) | GPR6HRH1CCR3KCNH2 | |
| SCHEMBL6523618 | 0.86 | PDE4B (0.42) | GPR6 | |
| SCHEMBL6520938 | 0.86 | GPR6 (0.38) | GPR6HRH1CCR3 | |
| SCHEMBL6518854 | 0.82 | NAMPT (0.44) | — | |
| SCHEMBL6524790 | 0.82 | NAMPT (0.44) | — | |
| SCHEMBL6518469 | 0.82 | PTGDR (0.43) | GPR6HRH1CCR3 | |
| SCHEMBL6524517 | 0.82 | GPR6 (0.41) | GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | F12, F2, C3AR1 | TBK1 3995/4885GPR6 1334/4885HRH1 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.