⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12952131 | 1.00 | — | — | |
| SCHEMBL8273362 | 0.82 | — | — | |
| SCHEMBL22911757 | 0.66 | — | — | |
| SCHEMBL15580549 | 0.65 | — | — | |
| SCHEMBL21899747 | 0.65 | — | — | |
| SCHEMBL8057663 | 0.62 | — | — | |
| SCHEMBL8295360 | 0.60 | — | — | |
| SCHEMBL19346247 | 0.60 | — | — | |
| SCHEMBL17383536 | 0.60 | — | — | |
| SCHEMBL19917483 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159374-A1 | 2'-Substituted nucleosides and oligonucleotide derivatives | NOVARTIS AG (CH) | 2005-07-21 | — | — | US | disclosed |
| US-6670468-B1 | Aminoalkylation at the 2' position | NOVARTIS AG (CH) | 2003-12-30 | — | — | US | disclosed |
| EP-0906329-B1 | 2'-SUBSTITUTED NUCLEOSIDES AND OLIGONUCLEOTIDE DERIVATIVES | NOVARTIS AG (CH) | 2003-10-08 | — | — | EP | disclosed |