Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 3/20 | 0.67 |
| ▸ | RAC2 | P15153 | 1/20 | 0.67 |
| ▸ | RAC3 | P60763 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4161227 | 0.85 | RAC1 (0.81) | RAC1RAC2RAC3PDK2EPHX2 | |
| SCHEMBL1461798 | 0.83 | RAC1 (0.73) | RAC1RAC2RAC3PDK2EPHX2 | |
| SCHEMBL1460427 | 0.81 | RAC1 (0.75) | RAC1RAC2RAC3PDK2KMT2A | |
| SCHEMBL1461351 | 0.81 | RAC1 (1.00) | RAC1RAC2RAC3PDK2EPHX2 | |
| SCHEMBL30798860 | 0.81 | RAC1 (1.00) | RAC1RAC2RAC3PDK2EPHX2 | |
| SCHEMBL6027115 | 0.80 | RAC1 (0.66) | RAC1RAC2RAC3PDK2KMT2A | |
| Hydrochloric Acid SCHEMBL29383079 | 0.80 | RAC1 (1.00) | RAC1RAC2RAC3PDK2EPHX2 | |
| Hydrochloric Acid SCHEMBL384979 | 0.80 | RAC1 (1.00) | RAC1RAC2RAC3PDK2EPHX2 | |
| SCHEMBL20678026 | 0.79 | RAC1 (0.65) | RAC1RAC2RAC3PDK2EPHX2 | |
| SCHEMBL20677974 | 0.78 | RAC1 (0.64) | RAC1RAC2RAC3PDK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597253-A2 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES, RETINOPATHIES AND ARTHRITIS | Exonhit Therapeutics S.A. (FR) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004076445-A2 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES, RETINOPATHIES AND ARTHRITIS | EXONHIT THERAPEUTICS SA (FR) | 2004-09-10 | — | — | WO | disclosed |