Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 16/20 | 0.73 |
| ▸ | HTR1A | P08908 | 11/20 | 0.73 |
| ▸ | DRD2 | P14416 | 9/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2979920 | 0.85 | HTR2B (0.74) | HTR2BHTR1ADRD2 | |
| SCHEMBL6649681 | 0.84 | HTR2B (0.73) | HTR2BHTR1ADRD2 | |
| SCHEMBL4754279 | 0.84 | HTR2B (1.00) | HTR2BHTR1ADRD2 | |
| SCHEMBL2987620 | 0.84 | HTR2B (0.72) | HTR2BHTR1ADRD2 | |
| SCHEMBL2983918 | 0.83 | HTR2B (0.70) | HTR2BHTR1ADRD2 | |
| SCHEMBL2734626 | 0.81 | HTR2B (0.68) | HTR2BHTR1ADRD2 | |
| SCHEMBL13940578 | 0.81 | HTR2B (0.68) | HTR2BHTR1ADRD2 | |
| SCHEMBL27782046 | 0.80 | HTR2B (0.70) | HTR2BHTR1ADRD2 | |
| SCHEMBL13499610 | 0.79 | HTR2B (0.65) | HTR2BHTR1ADRD2 | |
| SCHEMBL22113436 | 0.76 | HTR2B (0.73) | HTR2BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052723-A1 | USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2011-03-03 | — | — | US | claimed |
| US-20170112829-A1 | USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2017-04-27 | — | — | US | disclosed |