Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.54 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652143 | 0.93 | MLNR (0.67) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1094790 | 0.93 | MLNR (0.67) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL15737599 | 0.93 | SPPL2A (0.60) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL9223590 | 0.93 | SPPL2A (0.62) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL3471631 | 0.93 | MLNR (0.67) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1094789 | 0.93 | MLNR (0.67) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7467399 | 0.92 | SPPL2A (0.59) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL2185995 | 0.92 | SPPL2A (0.59) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL2186000 | 0.92 | SPPL2A (0.59) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL2186027 | 0.92 | SPPL2A (0.58) | SPPL2AMLNRABCB11LMNACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3657002-B2 | — | — | 2005-06-08 | — | — | JP | claimed |
| WO-1994004492-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | claimed |