Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533276 | 0.87 | CNR2 (0.38) | CHEK1CNR2 | |
| SCHEMBL6522000 | 0.86 | CHEK1 (0.41) | CHEK1CNR2 | |
| SCHEMBL6516690 | 0.86 | CHEK1 (0.42) | CHEK1CNR2 | |
| SCHEMBL6511866 | 0.85 | CHEK1 (0.38) | CHEK1CNR2 | |
| SCHEMBL6511094 | 0.81 | CHEK1 (0.41) | CHEK1CNR2 | |
| SCHEMBL6514165 | 0.79 | CHEK1 (0.39) | CHEK1CNR2 | |
| SCHEMBL6511027 | 0.78 | ATR (0.42) | CHEK1CNR2 | |
| SCHEMBL6507186 | 0.77 | HTR2C (0.41) | CHEK1CNR2 | |
| SCHEMBL6515376 | 0.77 | MAPT (0.41) | CHEK1CNR2 | |
| SCHEMBL6522817 | 0.76 | CHEK1 (0.39) | CHEK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245563-A1 | Chk-1 inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245563-A1 | Chk-1 inhibitors | CHKA, CHKB, CHEK1 | CHEK1 3/4885CNR2 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.