Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428646 | 0.82 | NR3C2 (0.50) | KDM4EALDH1A1HSD17B10MAPTTSHR | |
| SCHEMBL15428604 | 0.82 | NR3C2 (0.50) | KDM4EALDH1A1MAPTPARP1LMNA | |
| SCHEMBL15428637 | 0.82 | NR3C2 (0.51) | NPC1RAB9ASMN1; SMN2NR3C2 | |
| SCHEMBL15428729 | 0.82 | HSP90AA1 (0.36) | NPC1RIPK2TSHRLMNANR3C2 | |
| SCHEMBL15428659 | 0.78 | SCN9A (0.42) | KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL3168308 | 0.77 | POLB (0.53) | RIPK2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5334861 | 0.75 | NPC1 (0.51) | NPC1RIPK2KDM4EALDH1A1HPGD | |
| SCHEMBL31227600 | 0.75 | NPC1 (0.51) | NPC1RIPK2KDM4EALDH1A1HPGD | |
| SCHEMBL14334137 | 0.73 | FLT3 (0.48) | NPC1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4953424 | 0.72 | POLB (0.43) | NPC1RIPK2ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599463-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | E.I. du Pont de Nemours and Company (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004067528-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |