Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3491450 | 0.87 | AURKA (0.78) | AURKAAURKB | |
| SCHEMBL5485983 | 0.86 | AURKA (0.65) | AURKAAURKB | |
| SCHEMBL5489198 | 0.85 | AURKA (0.73) | AURKAAURKB | |
| SCHEMBL5489513 | 0.85 | AURKA (0.67) | AURKAAURKB | |
| SCHEMBL3489795 | 0.84 | AURKA (0.67) | AURKAAURKB | |
| SCHEMBL4298192 | 0.84 | AURKA (0.73) | AURKAAURKB | |
| SCHEMBL3488330 | 0.84 | AURKA (0.63) | AURKAAURKB | |
| SCHEMBL3490141 | 0.84 | AURKA (0.74) | AURKAAURKB | |
| SCHEMBL3488866 | 0.83 | AURKA (0.87) | AURKAAURKB | |
| SCHEMBL4294264 | 0.83 | AURKA (0.76) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578755-A1 | PHOSPHONOOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | AstraZeneca AB (SE) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058781-A1 | PHOSPHONOOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | ASTRAZENECA AB (SE) | 2004-07-15 | — | — | WO | disclosed |