Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006443 | 0.82 | KDM4E (0.50) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL23523301 | 0.82 | KDM4E (0.50) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL26923299 | 0.80 | KDM4E (0.48) | KDM4ETSHRPOLBPKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL23522810 | 0.80 | KDM4E (0.48) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL11981499 | 0.80 | KDM4E (0.48) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL3339210 | 0.79 | KDM4E (0.52) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL5472061 | 0.79 | KDM4E (0.56) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL1008455 | 0.77 | KDM4E (0.59) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL1010044 | 0.77 | KDM4E (0.54) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL1007625 | 0.77 | KDM4E (0.54) | KDM4ETSHRPOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501807-A1 | SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093245-A1 | SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | claimed |