Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.31 |
| ▸ | TUBB | P07437 | 3/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528097 | 0.94 | NTRK1 (0.33) | NOTUMMIFCA1CA2CA9 | |
| SCHEMBL6530108 | 0.90 | CAPN1 (0.32) | NOTUMMIFHDAC3TUBB4ATUBB | |
| SCHEMBL6527389 | 0.84 | NOTUM (0.34) | NOTUMMIFCA1CA2CA9 | |
| SCHEMBL6533849 | 0.82 | CAPN1 (0.33) | NOTUMMIFHDAC3TUBB4ATUBB | |
| SCHEMBL6533275 | 0.80 | MIF (0.34) | HPGDALOX15USP2LMNATP53 | |
| SCHEMBL6527807 | 0.80 | NOTUM (0.38) | NOTUMMIFCA1CA2CA9 | |
| SCHEMBL6528430 | 0.79 | NOTUM (0.37) | NOTUMMIFCA1CA2CA9 | |
| SCHEMBL6529698 | 0.78 | MIF (0.38) | NOTUMMIFCA1CA2CA9 | |
| SCHEMBL6531446 | 0.78 | NOTUM (0.37) | NOTUMMIFCA1CA2CA9 | |
| SCHEMBL6510881 | 0.77 | CA1 (0.43) | LMNASMN1; SMN2CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |