SCHEMBL65274

SCHEMBL65274

C1[N]CC2CC12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1224717 1.00
SCHEMBL788684 0.78
SCHEMBL4667800 0.78
SCHEMBL2705754 0.78
SCHEMBL1949501 0.67
SCHEMBL23866 0.67
SCHEMBL9049423 0.67
SCHEMBL9046191 0.67
SCHEMBL70863 0.65
SCHEMBL3202748 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182452-A1 6-PHENYL-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE DERIVATIVES AS PDE3A AND PDE3B INHIBITORS FOR TREATING CANCER BAYER AKTIENGESELLSCHAFT (DE) 2024-06-06 US claimed
EP-4339193-A1 COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF Innovstone Therapeutics Limited (CN) 2024-03-20 EP claimed
WO-2024051766-A1 MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-03-14 WO claimed
EP-4334295-A2 HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE Vigil Neuoscience, Inc. (US) 2024-03-13 EP claimed
US-20240043435-A1 TYK-2 INHIBITOR BEONE MEDICINES I GMBH (CH) 2024-02-08 US claimed
WO-2024028169-A1 NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2024-02-08 WO claimed
WO-2024008722-A2 TREM2 MODULATORS MUNA THERAPEUTICS APS (DK) 2024-01-11 WO claimed
WO-2023247590-A1 TRIAZOLOPYRIDINE AND BENZOISOXAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS ACTELION PHARMACEUTICALS LTD (CH) 2023-12-28 WO claimed
EP-4028401-B1 4,4A,5,7,8,8A-HEXAPYRIDO[4,3-B][1,4]OXAZIN-3-ONE COMPOUNDS AS MAGL INHIBITORS HOFFMANN LA ROCHE (CH) 2023-11-22 EP claimed
US-20230122651-A1 C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS TETRAPHASE PHARMACEUTICALS INC (US) 2023-04-20 US claimed
EP-0260555-A1 Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,2-diamine derivatives THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1988-03-23 EP claimed
EP-0224566-A1 ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES THE UPJOHN COMPANY (US) 1987-06-10 EP claimed
US-4632935-A Omega-(hydroxy-, ether and ester)-alkyl-2-amino-cycloalkyl- and cycloalkenyl amides as analgesics THE UPJOHN COMPANY (US) 1986-12-30 US claimed
WO-1986007257-A2 ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES THE UPJOHN COMPANY (US) 1986-12-18 WO claimed
EP-0176309-A2 Use of N-(2-aminocyclohexyl)benzeneacetamides in the treatment of cerebral ischemia THE UPJOHN COMPANY (US) 1986-04-02 EP claimed
EP-0167253-A1 Hydroxyalkylcycloalkylbenzeneacetamides and benzamides THE UPJOHN COMPANY (US) 1986-01-08 EP claimed
US-4508911-A Amine intermediates for analgesic compounds THE UPJOHN COMPANY (US) 1985-04-02 US claimed
EP-0129991-A1 2-Aminocycloalkenyl carboxamides and their tritiated 2-aminocycloalkyl carboxamide derivatives THE UPJOHN COMPANY (US) 1985-01-02 EP claimed
US-4463013-A Oxygen substituted amino-cyclohexyl-benzeneacetamides and -benzamides as water diuretic drugs THE UPJOHN COMPANY (US) 1984-07-31 US claimed
US-4438130-A Analgesic 1-oxa-, aza- and thia-spirocyclic compounds THE UPJOHN COMPANY (US) 1984-03-20 US claimed