Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494760 | 0.95 | KCNH2 (0.49) | KCNH2MC4RMEN1KMT2ALMNA | |
| SCHEMBL9136144 | 0.91 | KCNH2 (0.49) | KCNH2MC4RMEN1KMT2ALMNA | |
| SCHEMBL12793731 | 0.87 | KCNH2 (0.43) | KCNH2MC4RMEN1KMT2ALMNA | |
| SCHEMBL6560916 | 0.86 | KCNH2 (0.44) | KCNH2MC4RMEN1KMT2ALMNA | |
| SCHEMBL405660 | 0.85 | KCNH2 (0.44) | KCNH2MEN1KMT2ALMNATDP1 | |
| SCHEMBL14598859 | 0.85 | KCNH2 (0.44) | KCNH2MEN1KMT2ALMNATDP1 | |
| SCHEMBL438993 | 0.85 | KCNH2 (0.44) | KCNH2MEN1KMT2ALMNATDP1 | |
| SCHEMBL15388574 | 0.84 | KCNH2 (0.51) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28728445 | 0.83 | KCNH2 (0.45) | KCNH2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6520314 | 0.83 | SOAT1 (0.36) | LMNATDP1CYP2C19TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354512-B2 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-01-15 | — | — | US | disclosed |
| US-8354512-B2 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-01-15 | — | — | US | disclosed |
| US-20110065905-A1 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2011-03-17 | — | — | US | disclosed |
| US-20110065905-A1 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065905-A1 | Ligand and metal complex | CD74, SLC39A14, PYM1 | KCNH2 2609/4885MC4R 782/4885MEN1 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.