Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468999 | 0.89 | FFAR1 (0.38) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL6464982 | 0.88 | FFAR1 (0.41) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL6467870 | 0.88 | FFAR1 (0.41) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL6473864 | 0.86 | FFAR1 (0.40) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL2622472 | 0.84 | FFAR1 (0.34) | FFAR1CPT2TDP1 | |
| SCHEMBL3279503 | 0.83 | FFAR1 (0.34) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL2622469 | 0.82 | FFAR1 (0.37) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL3280332 | 0.80 | LPAR3 (0.32) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL8743769 | 0.79 | LPAR3 (0.33) | FFAR1CPT2TDP1S1PR4S1PR1 | |
| SCHEMBL3285610 | 0.76 | GRM4 (0.32) | S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497247-A2 | MIMICS OF ACYL COENZYME-A, COMPOSITIONS THEREOF, AND METHODS OF CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087108-A2 | MIMICS OF ACYL COENZYME-A, COMPOSITIONS THEREOF, AND METHODS OF CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2003-10-23 | — | — | WO | disclosed |