⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37672 | 0.69 | — | — | |
| SCHEMBL103660 | 0.65 | — | — | |
| SCHEMBL23326991 | 0.65 | — | — | |
| SCHEMBL27433396 | 0.65 | — | — | |
| SCHEMBL16851 | 0.54 | — | — | |
| Fluoride SCHEMBL27474380 | 0.54 | — | — | |
| SCHEMBL3387 | 0.49 | — | — | |
| Oxirane SCHEMBL9065683 | 0.46 | — | — | |
| SCHEMBL76442 | 0.46 | — | — | |
| SCHEMBL23908691 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 872 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166660-A1 | KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2024-05-23 | — | — | US | claimed |
| EP-4296273-A1 | ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME | Future Medicine Co., Ltd. (KR) | 2023-12-27 | — | — | EP | claimed |
| CN-117083286-A | Pair A 2A A is a 3 Adenosine derivatives having antagonism to adenosine receptor and process for preparing same | 未来制药有限公司 | 2023-11-17 | — | — | CN | claimed |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-10-12 | — | — | US | claimed |
| CN-112218849-B | Process for the preparation of amines | 巴斯夫欧洲公司 | 2023-08-18 | — | — | CN | claimed |
| US-20220389021-A1 | INHIBITORS OF KRAS G12C | BEONE MEDICINES I GMBH (CH) | 2022-12-08 | — | — | US | claimed |
| CN-114929706-A | Inhibitors of KRAS G12C | 百济神州有限公司 | 2022-08-19 | — | — | CN | claimed |
| WO-2022152233-A1 | KRAS G12C INHIBITORS | BEIGENE, LTD. (KY) | 2022-07-21 | — | — | WO | claimed |
| US-11390578-B2 | Method for synthesizing amines | BASF SE (DE) | 2022-07-19 | — | — | US | claimed |
| EP-3774716-B1 | PROCESS FOR THE PREPARATION OF AMINES | BASF SE (DE) | 2022-03-16 | — | — | EP | claimed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | claimed |
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | claimed |
| WO-1993014072-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| EP-0527817-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-24 | — | — | EP | claimed |
| WO-1991017157-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1991-11-14 | — | — | WO | claimed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | claimed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | claimed |
| EP-0405326-A2 | Silylated benzoic acid derivatives | Consortium für elektrochemische Industrie GmbH (DE) | 1991-01-02 | — | — | EP | claimed |
| EP-0404140-A2 | Silylated benzoic acid derivatives II | Consortium für elektrochemische Industrie GmbH (DE) | 1990-12-27 | — | — | EP | claimed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | claimed |