Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.74 |
| ▸ | MAP2K2 | P36507 | 17/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528379 | 0.87 | MAP2K1 (0.69) | MAP2K1MAP2K2 | |
| SCHEMBL5623601 | 0.85 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL6498903 | 0.82 | MAP2K1 (0.52) | MAP2K1MAP2K2ALDH1A1 | |
| SCHEMBL5624338 | 0.82 | MAP2K1 (0.81) | MAP2K1MAP2K2 | |
| Monoethanolamine SCHEMBL6528780 | 0.81 | MAP2K1 (0.75) | MAP2K1MAP2K2 | |
| SCHEMBL6528777 | 0.78 | MAP2K1 (0.74) | MAP2K1MAP2K2 | |
| SCHEMBL14418955 | 0.77 | MAP2K1 (0.69) | MAP2K1MAP2K2 | |
| SCHEMBL6528383 | 0.77 | MAP2K1 (0.68) | MAP2K1MAP2K2 | |
| SCHEMBL5622965 | 0.77 | MAP2K1 (0.82) | MAP2K1MAP2K2 | |
| SCHEMBL14418953 | 0.77 | MAP2K1 (0.75) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000818-A1 | 5-SUBSTITUTED-4-`(SUBSTITUTED PHENYL)!AMINO!-2-PYRIDONE DEVIATIVES FOR USE AS MEK INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-06 | — | — | WO | disclosed |