Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 7/20 | 0.83 |
| ▸ | PYGM | P11217 | 3/20 | 0.67 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TK1 | P04183 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175300 | 1.00 | TK2 (0.83) | TK2PYGMP2RY2SLC28A1SLC28A2 | |
| SCHEMBL2587710 | 1.00 | TK2 (0.83) | TK2PYGMP2RY2SLC28A1SLC28A2 | |
| SCHEMBL1628082 | 1.00 | TK2 (0.83) | TK2PYGMP2RY2SLC28A1SLC28A2 | |
| SCHEMBL2587708 | 1.00 | TK2 (0.83) | TK2PYGMP2RY2SLC28A1SLC28A2 | |
| SCHEMBL1628084 | 1.00 | TK2 (0.83) | TK2PYGMP2RY2SLC28A1SLC28A2 | |
| SCHEMBL2585320 | 0.91 | TK2 (0.69) | TK2PYGMP2RY2SLC28A1SLC28A2 | |
| SCHEMBL2577938 | 0.91 | TK2 (0.69) | TK2PYGMCYP1A2CYP3A4TSHR | |
| SCHEMBL2577941 | 0.91 | TK2 (0.69) | TK2PYGMCYP1A2CYP3A4TSHR | |
| SCHEMBL2577942 | 0.91 | TK2 (0.69) | TK2PYGMCYP1A2CYP3A4TSHR | |
| SCHEMBL2585319 | 0.91 | TK2 (0.69) | TK2PYGMP2RY2SLC28A1SLC28A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194174-B1 | EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD | UNIV ALBERTA SIMON FRASER UNI (CA) | 2005-09-21 | — | — | EP | disclosed |
| US-6780850-B1 | INHIBITING DEGRADATION OF A NUCLEIC ACID IN THE BLOOD COMPRISING ATTACHING STREPTAVIDIN OR A VARIANT THEREOF THAT RETAINS BIOTIN BINDING ACTIVITY TO SAID NUCLEIC ACID | TRIUMF (CA) | 2004-08-24 | — | — | US | disclosed |