Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13992665 | 0.78 | HDAC3 (0.45) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL2362973 | 0.77 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL13185669 | 0.76 | KDM4E (0.61) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL2492178 | 0.76 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL13992613 | 0.75 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL17201672 | 0.75 | ERN1 (0.48) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL7018973 | 0.75 | HDAC3 (0.73) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL17201533 | 0.74 | CDC7 (0.51) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL2694736 | 0.74 | CA12 (0.50) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL13994778 | 0.73 | CDC7 (0.61) | HDAC3HDAC4HDAC1HDAC6ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |