Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.88 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.88 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.88 |
| ▸ | HDAC7 | Q8WUI4 | 14/20 | 0.88 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.88 |
| ▸ | HDAC10 | Q969S8 | 14/20 | 0.88 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.88 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.88 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.88 |
| ▸ | HDAC9 | Q9UKV0 | 14/20 | 0.88 |
| ▸ | HDAC5 | Q9UQL6 | 14/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5903743 | 0.90 | HDAC1 (0.89) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5903808 | 0.88 | HDAC1 (0.88) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5904085 | 0.85 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL6529686 | 0.81 | HDAC1 (0.59) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5904041 | 0.79 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5903698 | 0.79 | HDAC1 (0.70) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5903812 | 0.77 | HDAC1 (0.81) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5903815 | 0.77 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5904044 | 0.76 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5904037 | 0.76 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |