Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12678517 | 1.00 | CNR2 (0.43) | CNR2OGAPSEN1PSEN2APH1B | |
| SCHEMBL21860132 | 0.84 | CYP2C9 (0.51) | OGAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14089093 | 0.84 | CYP2C9 (0.51) | OGAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3404691 | 0.82 | CNR2 (0.44) | CNR2CNR1ALDH1A1TRPV1EPHX1 | |
| SCHEMBL5133340 | 0.82 | CNR2 (0.44) | CNR2CNR1ALDH1A1TRPV1EPHX1 | |
| SCHEMBL3376556 | 0.82 | CNR2 (0.44) | CNR2CNR1ALDH1A1TRPV1EPHX1 | |
| SCHEMBL29315198 | 0.81 | CA1 (0.52) | OGAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12323203 | 0.81 | CNR2 (0.42) | CNR2CNR1TRPV1EPHX1PABPC1 | |
| SCHEMBL282958 | 0.80 | PSEN1 (0.52) | OGAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL282957 | 0.80 | PSEN1 (0.52) | OGAPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |