Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.58 |
| ▸ | TNNC1 | P63316 | 6/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.54 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.54 |
| ▸ | GPR183 | P32249 | 1/20 | 0.54 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6506423 | 0.99 | S1PR1 (0.57) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6526887 | 0.95 | S1PR1 (0.59) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL6528274 | 0.94 | S1PR1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6528028 | 0.88 | S1PR1 (0.61) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL6501505 | 0.87 | S1PR1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL13628896 | 0.85 | S1PR1 (0.69) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6530540 | 0.82 | S1PR1 (0.56) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6528364 | 0.81 | S1PR1 (0.61) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL3389424 | 0.81 | S1PR1 (0.73) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL3393720 | 0.81 | S1PR1 (0.73) | S1PR1TNNC1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |