Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110665 | 1.00 | TAAR1 (0.36) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL5103949 | 0.84 | TAAR1 (0.40) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL5110751 | 0.83 | TAAR1 (0.42) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL6525600 | 0.83 | TAAR1 (0.42) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL1479674 | 0.82 | TAAR1 (0.43) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL583539 | 0.82 | TAAR1 (0.43) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL4162306 | 0.82 | TAAR1 (0.43) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL5100536 | 0.80 | TAAR1 (0.36) | TAAR1CYP1A2ROCK2SCN10AKDM4E | |
| SCHEMBL4166302 | 0.80 | TACR1 (0.47) | TAAR1ROCK2SCN10AKDM4ERAB9A | |
| SCHEMBL5103917 | 0.80 | TACR1 (0.47) | TAAR1ROCK2SCN10AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |