Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | DAO | P14920 | 1/20 | 0.78 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.78 |
| ▸ | CES1 | P23141 | 5/20 | 0.64 |
| ▸ | CES2 | O00748 | 4/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL2330040 | 0.97 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28346663 | 0.97 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL7547480 | 0.95 | TSHR (0.70) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL9664197 | 0.88 | TSHR (0.88) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL28353337 | 0.88 | TSHR (0.75) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11154585 | 0.88 | TSHR (0.88) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL10457491 | 0.88 | TSHR (0.88) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL5731290 | 0.88 | TSHR (0.88) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL31657264 | 0.88 | TSHR (0.88) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28117481 | 0.88 | TSHR (0.88) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 875 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025063752-A1 | ORTHODONTIC ADHESIVE COMPOSITION AND METHOD FOR PREPARING SAME | 연세대학교 산학협력단 | 2025-03-27 | — | — | WO | claimed |
| CN-110845650-B | Slurry polymerization method for preparing bimodal distribution star-shaped branched butyl rubber by using terminal imino functionalized macromolecular branching agent | 北京石油化工学院 | 2022-09-16 | — | — | CN | claimed |
| CN-110845650-A | Slurry polymerization method for preparing bimodal distribution star-shaped branched butyl rubber by using terminal imino functionalized macromolecular branching agent | 北京石油化工学院 | 2020-02-28 | — | — | CN | claimed |
| CN-109650909-A | A kind of calcium phosphate bone induction bioceramic scaffold and preparation method thereof based on photocuring 3D printing technique | 四川大学 | 2019-04-19 | — | — | CN | claimed |
| CN-106118579-A | A kind of visible-light curing glue and preparation method thereof | 唐天 | 2016-11-16 | — | — | CN | claimed |
| CN-105021757-B | Matrix solid phase dispersion extraction-gas chromatogram the tandem mass spectrometry method for determining of 11 kinds of light triggers in solid-state food | 安徽农业大学 | 2016-08-24 | — | — | CN | claimed |
| CN-104194613-B | The ultraviolet curing chromatic that can recoat-painting silver powder coating and preparation method thereof | 江苏宏泰高分子材料有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-104004491-B | A kind of LED ultraviolet curing organic silicon packaging plastic and preparation method thereof | 江苏矽时代材料科技有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-104194001-B | A kind of preparation method of the macromolecules cross-linking agent for ultraviolet light cross-linking polyolefin | 中国科学技术大学 | 2016-07-13 | — | — | CN | claimed |
| CN-105694045-A | Functionalization method of divinyl double-plywood type oligomeric silsesquioxane | 烟台大学 | 2016-06-22 | — | — | CN | claimed |
| CN-1073947-A | Novel sunscreen metal complexes | RICHARDSON VICKS INC (US) | 1993-07-07 | — | — | CN | claimed |
| CN-1066182-A | Make human skin obtain a kind of artificial brown's stable emulsion composition | RICHARDSON VICKS INC (US) | 1992-11-18 | — | — | CN | claimed |
| CN-1063038-A | Retain in facial emulsion compositions | RICHARDSON VICKS INC (US) | 1992-07-29 | — | — | CN | claimed |
| US-5094943-A | Superoxide dimutase | BOEHRINGER MANNHEIM GMBH (DE) | 1992-03-10 | — | — | US | claimed |
| EP-0169397-B1 | PROCESS FOR PREPARATION OF ELECTROPHORESIS GEL MATERIAL | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-23 | — | — | EP | claimed |
| US-4900666-A | Colorimetric ethanol analysis method and test device | LIFESCAN, INC. (US) | 1990-02-13 | — | — | US | claimed |
| US-4863647-A | CONTROLLING CROSSLINKING OF ACRYLAMIDES; PHOTOINITIATORS, CURING AGENTS, MONITORING UV RADIATION | BAYLOR JR CHARLES (US) | 1989-09-05 | — | — | US | claimed |
| EP-0186134-B1 | MEANS FOR IMPROVING THE DETERMINATION OF OXIDASE REACTIONS PRODUCING HYDROGEN PEROXYDE, AND THEIR USE | Roche Diagnostics GmbH (DE) | 1989-02-15 | — | — | EP | claimed |
| EP-0169397-A1 | Process for preparation of electrophoresis gel material | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-29 | — | — | EP | claimed |
| US-4542202-A | EPOXY COMPOUND WITH A HYDROXY, MERCAPTO, OR HYDRAZIDE MODIFIED TERTIARY AMINE | AJINOMOTO CO., INC. (JP) | 1985-09-17 | — | — | US | claimed |