Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.64 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | CALML3 | P27482 | 7/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SDHA | P31040 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529626 | 0.89 | F10 (0.61) | F10MAOAMAOBCALML3CYP11B2 | |
| SCHEMBL6529624 | 0.89 | F10 (0.61) | F10MAOAMAOBCALML3CYP11B2 | |
| SCHEMBL8131862 | 0.89 | F10 (0.61) | F10MAOAMAOBCALML3CYP11B2 | |
| SCHEMBL8138382 | 0.87 | MAOB (0.52) | F10MAOAMAOBCALML3LMNA | |
| SCHEMBL8140551 | 0.85 | F10 (0.73) | F10MAOAMAOBCALML3LMNA | |
| SCHEMBL6528285 | 0.84 | F10 (0.49) | F10MAOAMAOBCALML3LMNA | |
| SCHEMBL6528284 | 0.84 | F10 (0.49) | F10MAOAMAOBCALML3LMNA | |
| SCHEMBL8140856 | 0.84 | F10 (0.71) | F10MAOAMAOBCALML3LMNA | |
| SCHEMBL8145429 | 0.84 | F10 (0.68) | F10MAOAMAOBCALML3LMNA | |
| SCHEMBL8128440 | 0.84 | F10 (0.73) | F10MAOAMAOBCALML3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |
| EP-1049692-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | Bayer Aktiengesellschaft (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037641-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |