⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573989 | 0.72 | — | — | |
| SCHEMBL666898 | 0.67 | — | — | |
| Butadiene SCHEMBL10873016 | 0.60 | — | — | |
| SCHEMBL10790106 | 0.60 | — | — | |
| SCHEMBL27490887 | 0.60 | — | — | |
| SCHEMBL10890930 | 0.57 | — | — | |
| SCHEMBL6902462 | 0.57 | — | — | |
| SCHEMBL484322 | 0.57 | — | — | |
| SCHEMBL10817609 | 0.57 | — | — | |
| SCHEMBL11820116 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005508365-A | — | — | 2005-03-31 | — | — | JP | claimed |
| EP-1441772-A2 | POLYMER CONJUGATES OF PROTEIN KINASE C INHIBITORS | Nektar Therapeutics Al, Corporation (US) | 2004-08-04 | — | — | EP | claimed |
| WO-2003037384-A2 | POLYMER CONJUGATES OF PROTEIN KINASE C INHIBITORS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2003-05-08 | — | — | WO | claimed |
| CN-115003663-B | Novel heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117534600-A | Isothiocyano trans-cyclohexyl biphenyl liquid crystal compound, and preparation method and application thereof | 武汉轻工大学 | 2024-02-09 | — | — | CN | disclosed |
| US-20130123253-A1 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2013-05-16 | — | — | US | disclosed |
| CN-1230434-C | Indazolyl-substituted pyrroline compounds as kinase inhibitor | ORTHO MCNEL PHARMACEUTICAL INC (US) | 2005-12-07 | — | — | CN | disclosed |
| CN-1489586-A | Indazolyl-substituted pyrroline compounds as kinase inhibitor | ����-������ҩƷ��˾ | 2004-04-14 | — | — | CN | disclosed |