Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528683 | 0.83 | DPP4 (0.54) | DPP4DPP8DPP7DPP9SPHK1 | |
| SCHEMBL6530995 | 0.81 | HSD17B10 (0.43) | DPP4DPP8DPP7 | |
| SCHEMBL6530776 | 0.81 | DPP4 (0.66) | DPP4DPP8DPP7 | |
| SCHEMBL6510648 | 0.81 | DPP4 (0.61) | DPP4DPP8DPP7DPP9CNR2 | |
| SCHEMBL6531210 | 0.80 | DPP4 (0.55) | DPP4DPP8DPP7DPP9CNR2 | |
| SCHEMBL6530178 | 0.80 | DPP4 (0.46) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6512307 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP7DPP9CNR2 | |
| SCHEMBL6527898 | 0.79 | DPP4 (0.50) | DPP4DPP8DPP7 | |
| SCHEMBL6532358 | 0.78 | DPP4 (0.74) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6531563 | 0.78 | DPP4 (0.70) | DPP4DPP8DPP7DPP9CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |