Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | APEX1 | P27695 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334635 | 0.85 | CYP3A4 (0.61) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL27843119 | 0.84 | ESR1 (0.50) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL12762398 | 0.82 | MAPT (0.62) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL13698041 | 0.81 | CYP3A4 (0.47) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL19472347 | 0.79 | BLM (0.69) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL7146918 | 0.79 | BLM (0.69) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL2728020 | 0.77 | TSHR (0.76) | TSHRCYP3A4BLMPMP22NPSR1 | |
| SCHEMBL14456692 | 0.76 | KDM4E (0.74) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL16208744 | 0.76 | KDM4E (0.74) | TSHRCYP3A4ADRB2TDP1MAPT | |
| SCHEMBL31222316 | 0.76 | ESR1 (0.48) | CYP3A4TDP1MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003140-A1 | 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |