Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374991 | 1.00 | TDP1 (0.51) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL873242 | 0.85 | TDP1 (0.58) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| Ethane SCHEMBL17791907 | 0.83 | TDP1 (0.61) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL8650694 | 0.83 | TDP1 (0.46) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL6154152 | 0.83 | TDP1 (0.46) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL7574669 | 0.82 | TDP1 (0.50) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL7583499 | 0.82 | TDP1 (0.50) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL10915080 | 0.82 | TDP1 (0.50) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL3264927 | 0.82 | TDP1 (0.50) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL7194323 | 0.82 | TDP1 (0.50) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050069995-A1 | (R)-hydroxycarboxylic acid producing recombinant microorganism and process for preparing (r)-hydroxycarboxylic acid using the same | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-03-31 | — | — | US | disclosed |
| US-20030143703-A1 | Recombinant microorganism expressing polyhydroxyalkanoate biosynthesis enzyme and intracellular PHA depolymerase | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-07-31 | — | — | US | disclosed |
| WO-2003046159-A1 | (R)-HYDROXYCARBOXYLIC ACID PRODUCING RECOMBINANT MICROORGANISM AND PROCESS FOR PREPARING (R)-HYDROXYCARBOXYLIC ACID USING THE SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-05 | — | — | WO | disclosed |