Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 6/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527906 | 1.00 | MIF (0.38) | MIFNOTUMRBP4CAPN1SIRT1 | |
| SCHEMBL6529591 | 0.88 | MIF (0.35) | MIFNOTUMCAPN1SIRT1RXRA | |
| SCHEMBL6529895 | 0.84 | MIF (0.37) | MIFNOTUMSIRT1 | |
| SCHEMBL6527855 | 0.83 | MIF (0.36) | MIFNOTUM | |
| SCHEMBL6528820 | 0.80 | NOTUM (0.41) | MIFNOTUM | |
| SCHEMBL6619473 | 0.80 | MIF (0.37) | MIFNOTUMRXRAGRIN1GRIN2B | |
| SCHEMBL6527383 | 0.80 | NOTUM (0.40) | MIFNOTUMRBP4RXRAGRIN1 | |
| SCHEMBL6532028 | 0.80 | NOTUM (0.40) | MIFNOTUMRBP4RXRAGRIN1 | |
| SCHEMBL6528832 | 0.79 | MIF (0.39) | MIFNOTUMRXRAGRIN1GRIN2B | |
| SCHEMBL6529616 | 0.79 | NOTUM (0.35) | MIFNOTUMRXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | claimed |