Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.59 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.59 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12773610 | 0.92 | SMN1; SMN2 (0.75) | SMN1; SMN2PTPN1POLBTAAR1ALDH1A1 | |
| SCHEMBL6531735 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2PTPN1POLBALDH1A1KMT2A | |
| SCHEMBL5302419 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2PTPN1POLBTAAR1ALDH1A1 | |
| SCHEMBL9853024 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2PTPN1POLBALDH1A1KMT2A | |
| SCHEMBL11441525 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2PTPN1POLBTAAR1ALDH1A1 | |
| SCHEMBL7357508 | 0.85 | POLB (0.69) | SMN1; SMN2PTPN1POLBALDH1A1KMT2A | |
| SCHEMBL4583404 | 0.85 | SMN1; SMN2 (0.75) | SMN1; SMN2PTPN1TAAR1ALDH1A1KMT2A | |
| SCHEMBL3656068 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2PTPN1POLBTAAR1ALDH1A1 | |
| SCHEMBL23417615 | 0.84 | POLB (0.77) | SMN1; SMN2POLBALDH1A1KMT2AMAPT | |
| SCHEMBL5805271 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2PTPN1POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059605-A1 | Chemically modified metabolites of regulatory peptides and methods of producing and using same | THERATECHNOLOGIES INC. (CA) | 2005-03-17 | — | — | US | disclosed |
| WO-2004067548-A2 | CHEMICALLY MODIFIED METABOLITES OF REGULATORY PEPTIDES AND METHODS OF PRODUCING AND USING SAME | THERATECHNOLOGIES INC. (CA) | 2004-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059605-A1 | Chemically modified metabolites of regulatory peptides and methods of producing and using same | PTMS, DPP7, GIPR | SMN1; SMN2 4203/4885PTPN1 568/4885POLB 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.