SCHEMBL6531270

SCHEMBL6531270

CCCCCN(N)c1ccc(OC)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 5/20 0.45
CNR2 P34972 1/20 0.44
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
TLR8 Q9NR97 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
EGFR P00533 1/20 0.38
PDGFRB P09619 1/20 0.38
KDR P35968 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6528985 0.84 KDM4E (0.50) CA12CA1CA2CA7CA9
SCHEMBL24359339 0.81 CNR2 (0.52) AOC3CNR2CA12CA1CA2
SCHEMBL13261439 0.80 MAPT (0.47) AOC3CNR2CA12CA1CA2
SCHEMBL28040051 0.79 MAPT (0.47) TLR8MAPK1TDP1LMNACYP1A2
SCHEMBL2775693 0.79 AOC3 (0.52) AOC3CA12CA1CA2CA7
SCHEMBL20746927 0.79 CNR2 (0.47) AOC3CNR2CA12CA1CA2
SCHEMBL10787032 0.79 CNR2 (0.47) AOC3CNR2CA12CA1CA2
SCHEMBL14447064 0.79 CNR2 (0.47) AOC3CNR2CA12CA1CA2
SCHEMBL10786365 0.79 CNR2 (0.47) AOC3CNR2CA12CA1CA2
SCHEMBL28144592 0.78 CYP1A2 (0.40) MAPK1TDP1LMNACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082866-A2 SUBSTITUTED 1, 2, 4- TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS PFIZER LIMITED (GB) 2005-09-09 WO disclosed