Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528433 | 0.86 | PRKDC (0.31) | PRKDC | |
| SCHEMBL6530172 | 0.81 | — | — | |
| SCHEMBL6529057 | 0.80 | — | — | |
| SCHEMBL6672501 | 0.74 | KCNH2 (0.31) | ALDH1A1 | |
| SCHEMBL5485592 | 0.74 | — | — | |
| SCHEMBL6669192 | 0.73 | KCNH2 (0.33) | MAPK1 | |
| SCHEMBL6372572 | 0.73 | KCNH2 (0.44) | ALDH1A1 | |
| SCHEMBL6670112 | 0.73 | KCNH2 (0.32) | ALDH1A1 | |
| SCHEMBL6670430 | 0.72 | KCNH2 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL6669644 | 0.72 | KCNH2 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026145-A2 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | claimed |