Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529263 | 0.82 | S1PR1 (0.50) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6527719 | 0.82 | S1PR1 (0.65) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6507059 | 0.80 | S1PR1 (0.51) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6508458 | 0.80 | S1PR1 (0.59) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6508336 | 0.79 | S1PR1 (0.47) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6508260 | 0.79 | S1PR1 (0.61) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6507062 | 0.78 | S1PR1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6504336 | 0.78 | S1PR1 (0.57) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL12337241 | 0.74 | S1PR1 (0.73) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8495816 | 0.74 | S1PR1 (0.73) | S1PR1TNNC1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |