SCHEMBL6532119

SCHEMBL6532119

[O]C1CCOCC(Oc2c[c]ccc2)CCOC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 1/20 0.34
NTRK3 Q16288 1/20 0.34
NTRK2 Q16620 1/20 0.34
GRM5 P41594 4/20 0.33
ACACB O00763 3/20 0.33
IDO1 P14902 1/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
PDE4D Q08499 4/20 0.31
PDE4A P27815 3/20 0.31
PDE4B Q07343 3/20 0.31
PDE4C Q08493 3/20 0.31
CPT2 P23786 2/20 0.31
CPT1A P50416 2/20 0.31
ACACA Q13085 1/20 0.31
HRH3 Q9Y5N1 2/20 0.31
CTSL P07711 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16987099 0.92 NTRK1 (0.36) NTRK1NTRK3NTRK2GRM5ACACB
SCHEMBL6531354 0.90 KAT2B (0.30) CPT2CPT1A
SCHEMBL6531901 0.83
SCHEMBL6531997 0.83 ACACB (0.38) GRM5ACACBPDE4DPDE4APDE4B
SCHEMBL16987030 0.82 KAT2B (0.37) GRM5ACACBHRH3
SCHEMBL6529793 0.82
SCHEMBL14814235 0.79 HRH1 (0.32)
SCHEMBL6531596 0.74 PDE4D (0.33) NTRK1NTRK3NTRK2GRM5PDE4D
SCHEMBL514610 0.74 HRH1 (0.42) HRH3
SCHEMBL4725119 0.73 ACACB (0.39) GRM5ACACBIDO1PDE4DPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8487071-B2 Polyether polymer and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-16 US disclosed
US-20110065889-A1 POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed